The aim of this paper is to indicate the effects of the global economic crisis on the innovation activity of industrial enterprises, including SMEs, in the Kujawsko-Pomorskie Voivodship. To identify those effects, statistical data for years 2005-2009 was used for analysis: expenditures on innovation activities of enterprises; the percentage of enterprises that made expenditures on innovation activities; the percentage of enterprises that have introduced innovations; the share of sold production of new/significantly improved products in total sales value; the share of net revenues from innovative products in net revenues from the total sale; the percentage of enterprises that cooperated in the field of innovation; investment in R+D of enterprises; and the number of people associated with R+D in enterprises. The results of the analysis indicate that in 2005–2009 the intensity of innovation activity of enterprises in the Kujawsko-Pomorskie Voivodship significantly decreased. It may be one of the main barriers to the development of the region in the coming years.
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